Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.68 |
| ▸ | THPO | P40225 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | NPY1R | P25929 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | NPY2R | P49146 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634268 | 1.00 | LMNA (0.68) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL5503588 | 0.89 | SLC29A1 (0.60) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL5503581 | 0.89 | ADORA1 (0.59) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL5962910 | 0.88 | ADORA3 (0.68) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL5962916 | 0.88 | ADORA3 (0.68) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL233209 | 0.86 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL17889837 | 0.86 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL19485512 | 0.86 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL21953578 | 0.86 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO | |
| SCHEMBL9945526 | 0.86 | LMNA (0.72) | LMNASLC29A1TSHRNFKB1THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567841-A2 | Fluorescently marked compounds, their preparation and use | MERCK PATENT GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |