SCHEMBL9565267

SCHEMBL9565267

Nc1cc(Oc2ccccc2-c2ccccc2)cc(C(F)(F)F)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.56
NCOA3 Q9Y6Q9 1/20 0.56
AR P10275 1/20 0.49
TACR1 P25103 3/20 0.41
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
MET P08581 1/20 0.39
ADORA2A P29274 1/20 0.39
BRD4 O60885 1/20 0.39
ALOX5AP P20292 1/20 0.38
FEN1 P39748 1/20 0.38
BACE1 P56817 1/20 0.38
DDB1 Q16531 1/20 0.38
CRBN Q96SW2 1/20 0.38
PTGDR2 Q9Y5Y4 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7182073 0.86 TSHR (0.46) ARADORA2ACYP1A2CYP2C19NPSR1
SCHEMBL25263928 0.82 MAPT (0.39) NCOA1NCOA3ARTACR1MET
SCHEMBL28400561 0.81 MEN1 (0.51) SLC6A2SLC6A4ADORA2ACYP1A2CYP2C9
SCHEMBL8581109 0.80 MEN1 (0.58) ARADORA2ACYP1A2CYP2C9CYP2C19
SCHEMBL8138086 0.79 TSHR (0.46) ADORA2ADDB1CRBNCYP1A2CYP2C19
SCHEMBL28672016 0.79 NCOA1 (0.62) NCOA1NCOA3ARBRD4BACE1
SCHEMBL16311885 0.78 AR (0.44) NCOA1NCOA3ARTACR1BACE1
SCHEMBL8741858 0.77 NCOA1 (0.56) NCOA1NCOA3ARBRD4ALOX5AP
SCHEMBL7186658 0.76 ALDH1A1 (0.47) L3MBTL1TSHRMAPK1MEN1NPC1
SCHEMBL3642350 0.75 NCOA1 (0.67) NCOA1NCOA3ARBRD4SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0565352-A2 Aromatic diamine and polyimde, and preparation process of same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-10-13 EP claimed
CN-117028876-A LED filament and LED bulb lamp 嘉兴山蒲照明电器有限公司 2023-11-10 CN disclosed
CN-116891571-A Organosilicon modified polyimide resin composition and application thereof 嘉兴山蒲照明电器有限公司 2023-10-17 CN disclosed
CN-109517172-B Organosilicon modified polyimide resin composition and application thereof 嘉兴山蒲照明电器有限公司 2023-08-29 CN disclosed
CN-109973833-B LED filament and LED bulb 嘉兴山蒲照明电器有限公司 2023-03-28 CN disclosed
CN-214663776-U LED filament and LED bulb 嘉兴山蒲照明电器有限公司 2021-11-09 CN disclosed
CN-214332357-U Light-emitting diode filament and light-emitting diode bulb lamp 嘉兴山蒲照明电器有限公司 2021-10-01 CN disclosed
CN-214147468-U LED filament and LED bulb 嘉兴山蒲照明电器有限公司 2021-09-07 CN disclosed
CN-110081323-B LED filament and LED bulb JIAXING SUPER LIGHTING ELECTRIC APPLIANCE CO.,LTD. (CN) 2021-08-31 CN disclosed
CN-213629939-U Light-emitting diode filament and light-emitting diode bulb lamp 嘉兴山蒲照明电器有限公司 2021-07-06 CN disclosed
CN-213452941-U LED filament and LED bulb 嘉兴山蒲照明电器有限公司 2021-06-15 CN disclosed
CN-211952283-U LED filament and LED bulb 嘉兴山蒲照明电器有限公司 2020-11-17 CN disclosed
CN-110145698-B LED bulb lamp with organic silicon modified polyimide resin composition as filament base layer 浙江山蒲照明电器有限公司 2020-09-25 CN disclosed
CN-211475542-U LED filament and LED bulb 嘉兴山蒲照明电器有限公司 2020-09-11 CN disclosed
CN-211010831-U L ED bulb lamp 嘉兴山蒲照明电器有限公司 2020-07-14 CN disclosed
CN-108976135-B Flexible diamine monomer, preparation method thereof and application thereof in preparation of polyimide 吉林大学 2020-04-28 CN disclosed
CN-104497309-B High-frequency high-binding-force polyimide film and preparation method thereof 珠海亚泰电子科技有限公司 2017-05-24 CN disclosed
CN-104497572-B Colorless high-transparency polyimide film and preparation method thereof 珠海亚泰电子科技有限公司 2016-08-24 CN disclosed