SCHEMBL28672016

SCHEMBL28672016

FC(F)(F)c1ccc(Oc2ccccc2-c2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.62
NCOA3 Q9Y6Q9 1/20 0.62
AR P10275 1/20 0.56
KIF11 P52732 1/20 0.52
BACE1 P56817 2/20 0.47
PTGS2 P35354 1/20 0.46
FFAR4 Q5NUL3 2/20 0.44
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
PTGDR2 Q9Y5Y4 2/20 0.43
SCN9A Q15858 1/20 0.41
BRD4 O60885 1/20 0.41
CYP19A1 P11511 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
FFAR1 O14842 2/20 0.40
MAPK14 Q16539 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25429460 0.87 KIF11 (0.53) NCOA1NCOA3ARKIF11BACE1
SCHEMBL3992772 0.87 AR (0.48) NCOA1NCOA3ARKIF11BACE1
SCHEMBL25343498 0.85 CYP2C8 (0.53) NCOA1NCOA3BACE1PTGS2FFAR4
SCHEMBL25429840 0.85 PTGS2 (0.51) NCOA1NCOA3ARKIF11BACE1
SCHEMBL30519278 0.85 CYP2C8 (0.53) NCOA1NCOA3BACE1PTGS2FFAR4
SCHEMBL25977697 0.84 SLC6A4 (0.45) NCOA1NCOA3ARKIF11BACE1
SCHEMBL28638978 0.83 L3MBTL1 (0.52) KIF11ALDH1A1TSHRMAPK14
SCHEMBL25973310 0.82 PTGS2 (0.45) NCOA1NCOA3ARKIF11BACE1
SCHEMBL6098760 0.82 KIF11 (0.43) NCOA1NCOA3ARKIF11BACE1
SCHEMBL25430418 0.81 PTGS2 (0.72) PTGS2PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113874420-A Resin film, metal-clad laminate, and method for producing same 日铁化学材料株式会社 2021-12-31 CN disclosed