Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199593 | 0.82 | CYSLTR1 (0.56) | GPBAR1CYSLTR1CYSLTR2ALOX5PDE10A | |
| SCHEMBL8617516 | 0.82 | CYSLTR1 (0.64) | GPBAR1CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL8588067 | 0.80 | CYSLTR1 (0.53) | GPBAR1CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL8616407 | 0.79 | CYSLTR1 (0.66) | GPBAR1CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL8305692 | 0.78 | CYSLTR1 (0.48) | GPBAR1CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL8538426 | 0.77 | CYSLTR1 (0.65) | GPBAR1CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL9202041 | 0.75 | ALOX5AP (0.55) | GPBAR1CYSLTR1CYSLTR2ALOX5CYP1A2 | |
| SCHEMBL9205037 | 0.75 | ALOX5AP (0.55) | GPBAR1CYSLTR1CYSLTR2CYP1A2PDE10A | |
| SCHEMBL8538241 | 0.74 | CYSLTR1 (0.67) | GPBAR1CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL9203135 | 0.73 | CYSLTR1 (0.65) | GPBAR1CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539117-A1 | Compounds useful as leukotriene antagonists | LILLY INDUSTRIES LIMITED (GB) | 1993-04-28 | — | — | EP | disclosed |