Terephthalamide

Terephthalamide

SCHEMBL9565530

NC(=O)c1ccc(C(N)=O)cc1.NNC(=O)c1ccc(N)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.57
HIF1A Q16665 2/20 0.57
MPO P05164 2/20 0.57
KDM5A P29375 1/20 0.57
BLM P54132 1/20 0.57
GFER P55789 1/20 0.57
PMP22 Q01453 1/20 0.57
PARP10 Q53GL7 1/20 0.57
KDM4E B2RXH2 5/20 0.55
MAPT P10636 3/20 0.55
LMNA P02545 3/20 0.55
ALDH1A1 P00352 3/20 0.55
OGG1 O15527 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
TDP1 Q9NUW8 2/20 0.53
MEN1 O00255 1/20 0.53
POLB P06746 1/20 0.53
PKM P14618 1/20 0.53
APEX1 P27695 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL328628 0.91 HIF1A (0.67) CYP3A4HIF1AMPOKDM5ABLM
SCHEMBL3780335 0.91 CYP3A4 (0.67) CYP3A4HIF1AMPOKDM5ABLM
Terephthalamide SCHEMBL437011 0.84 PARP10 (0.74) CYP3A4BLMPMP22PARP10MAPT
SCHEMBL56532 0.84 PARP10 (0.74) CYP3A4BLMPMP22PARP10MAPT
SCHEMBL7642130 0.84 PARP10 (0.74) CYP3A4BLMPMP22PARP10MAPT
Terephthalamide SCHEMBL2427917 0.83 MAPT (0.67) CYP3A4HIF1AMPOKDM5ABLM
Water SCHEMBL6343332 0.82 PARP10 (0.71) CYP3A4BLMPMP22PARP10MAPT
Hydrochloric Acid SCHEMBL4408462 0.82 PARP10 (0.71) CYP3A4BLMPMP22PARP10MAPT
SCHEMBL343630 0.82 MPO (0.80) CYP3A4HIF1AMPOKDM5ABLM
SCHEMBL2678949 0.82 MPO (0.80) CYP3A4HIF1AMPOKDM5ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5246735-A Fraying resistance, belts, polyurethane film by impregnating fibers with hydroxy-terminated rubber and an isocyanate-terminated rubber TEIJIN LIMITED (JP) 1993-09-21 US disclosed
EP-0537462-A1 Process for producing rubber-reinforcing aromatic polyamide multifilament yarn TEIJIN LIMITED (JP) 1993-04-21 EP disclosed