SCHEMBL328628

SCHEMBL328628

NNC(=O)c1ccc(N)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.67
MPO P05164 2/20 0.67
CYP3A4 P08684 2/20 0.67
BLM P54132 2/20 0.67
PMP22 Q01453 2/20 0.67
KDM5A P29375 1/20 0.67
GFER P55789 1/20 0.67
KDM4E B2RXH2 4/20 0.64
MAPT P10636 4/20 0.64
LMNA P02545 4/20 0.64
ALDH1A1 P00352 3/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
OGG1 O15527 1/20 0.64
MEN1 O00255 1/20 0.61
POLB P06746 1/20 0.61
PKM P14618 1/20 0.61
APEX1 P27695 1/20 0.61
KMT2A Q03164 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
SLC22A6 Q4U2R8 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL9565530 0.91 CYP3A4 (0.57) HIF1AMPOCYP3A4BLMPMP22
SCHEMBL343630 0.89 MPO (0.80) HIF1AMPOCYP3A4BLMPMP22
SCHEMBL2678949 0.89 MPO (0.80) HIF1AMPOCYP3A4BLMPMP22
SCHEMBL11132687 0.88 PARP10 (0.63) HIF1AMPOCYP3A4BLMPMP22
Dioxane SCHEMBL28874690 0.88 HIF1A (0.53) HIF1AMPOCYP3A4BLMPMP22
SCHEMBL28188923 0.87 MPO (0.76) HIF1AMPOCYP3A4BLMPMP22
SCHEMBL23918991 0.82 LMNA (0.64) HIF1ACYP3A4BLMPMP22KDM4E
SCHEMBL11134828 0.82 MPO (0.70) HIF1AMPOCYP3A4BLMPMP22
SCHEMBL9921348 0.82 POLB (0.64) HIF1AMPOCYP3A4BLMPMP22
SCHEMBL752600 0.82 MPO (0.70) HIF1AMPOCYP3A4BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 957 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3789395-B1 PEGYLATION OF FGF21 BRISTOL MYERS SQUIBB CO (US) 2025-08-27 EP claimed
CN-120059070-A Preparation method of hydrogel with covalent organic framework-polymer mechanical interlocking structure 河北工业大学 2025-05-30 CN claimed
CN-119499874-B Loose nanofiltration membrane and preparation method and application thereof 天津工业大学 2025-05-13 CN claimed
CN-119812514-A Self-adaptive active regeneration zinc cathode-electrolyte interface stabilization method 广西大学 2025-04-11 CN claimed
CN-119725717-A Nitrogen-rich solid electrolyte and preparation method and application thereof 内蒙古工业大学 2025-03-28 CN claimed
CN-119674192-A PVDF-based organic-inorganic composite polymer solid electrolyte and preparation method and application thereof 山东创鲁先进电池科技有限公司 2025-03-21 CN claimed
CN-119499874-A Loose nanofiltration membrane and preparation method and application thereof 天津工业大学 2025-02-25 CN claimed
CN-119351754-A Recycling treatment method of copper-containing sludge 江西省金瑞环保科技有限公司 2025-01-24 CN claimed
CN-115028857-B Swelling-resistant high-strength and toughness hydrogel with adjustable mechanical and fluorescence properties, and preparation method and application thereof 华南理工大学 2024-12-27 CN claimed
CN-118002203-A Preparation method and application of spinel-covalent organic framework composite material 河北工业大学 2024-05-10 CN claimed
US-5514676-A TO INHIBIT THE FORMATION OF ADVANCED GLYCOSLYATION PRODUCTS BY THE NONENZYMATIC CROSSLINKING OF PROTEINS WITH REDUCING SUGARS, USED IN FOOD PRESERVATION AND TO PREVENT PROTEIN AGING IN COLLAGEN OR LENSES IN THE EYE PRESERVATION THE ROCKEFELLER UNIVERSITY (US) 1996-05-07 US claimed
US-5498546-A PHOTOMETRICALLY MEASURING AMOUNT OF REDUCING SUGAR BY REACTION WITH COLOR-FORMING REAGENT TO DETERMINE THE CONCENTRATION OF DETERGENT IN WASH LIQUOR HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-03-12 US claimed
US-5476849-A Inhibiting advanced glycosylation and/or crosslinking of target protein THE ROCKEFELLER UNIVERSITY (US) 1995-12-19 US claimed
EP-0510818-B1 Blends of polybenzimidazoles and aromatic polyamides, aromatic polyamide-hydrazides or aromatic polyamides containing heterocyclic linkages HOECHST CELANESE CORP (US) 1995-12-13 EP claimed
EP-0339264-B1 Compounds for the introduction of a mercapto group to tyrosin BOEHRINGER MANNHEIM GMBH (DE) 1994-08-03 EP claimed
EP-0581904-A4 METHOD OF INHIBITING FIBROSIS UNIV DUKE (US) 1994-05-25 EP claimed
EP-0581904-A1 METHOD OF INHIBITING FIBROSIS. UNIV DUKE (US) 1994-02-09 EP claimed
WO-1992017065-A2 METHOD OF INHIBITING FIBROSIS DUKE UNIVERSITY (US) 1992-10-15 WO claimed
US-4227885-A TREATMENT WITH LIQUID TERTIARY AMINE TO IMPROVE TENSILE PROPERTIES MONSANTO COMPANY (US) 1980-10-14 US claimed
US-4180614-A POLYAMIDES, POLYIMIDES, POLYAMIDEIMIDE COPOLYMERS, POLYHYDTAZIDES, POLYAZOMETHINES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-12-25 US claimed