SCHEMBL9565665

SCHEMBL9565665

NC(=O)COc1nc2cccc(Cl)c2s1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 1/20 0.43
ALOX5 P09917 1/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
HSP90AA1 P07900 6/20 0.39
HSP90AB1 P08238 6/20 0.39
POLB P06746 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
AKR1B1 P15121 1/20 0.38
TYK2 P29597 2/20 0.37
ACACA Q13085 1/20 0.36
PRF1 P14222 1/20 0.36
PARP1 P09874 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9301532 0.83 MEN1 (0.40) KMT2AMEN1PTGS1PTGS2HSP90AA1
SCHEMBL9585282 0.81 SMN1; SMN2 (0.51) KMT2AMEN1POLBRXFP1
SCHEMBL9590384 0.79 MEN1 (0.69) ALOX5KMT2AMEN1POLB
SCHEMBL11206376 0.79 PSMB8 (0.47) PSMB8ALOX5KMT2APTGS1PTGS2
SCHEMBL9281180 0.78 KMT2A (0.61) KMT2AMEN1PTGS1PTGS2
SCHEMBL9422384 0.70 PSMB8 (0.42) PSMB8KMT2APOLBRXFP1ACACA
SCHEMBL9037853 0.69 PSMB8 (0.43) PSMB8ALOX5KMT2AHSP90AA1HSP90AB1
SCHEMBL9280327 0.68 GAA (0.49) KMT2AMEN1
SCHEMBL9676001 0.68 PSMB8 (0.56) PSMB8ALOX5HSP90AA1HSP90AB1HDAC3
SCHEMBL6203335 0.67 HTT (0.53) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0510479-A1 7-Chloro-benzothiazolyloxyacetamide BAYER AG (DE) 1992-10-28 EP claimed
EP-0573882-A1 2-(7-chlor-2-benzoxazolyloxy)-acetamide and their use as herbicides BAYER AG (DE) 1993-12-15 EP disclosed
US-5234896-A Herbicidal 7-chloro-benzothiazolyloxyacetamides BAYER AKTIENGESELLSCHAFT (DE) 1993-08-10 US disclosed
US-5234896-A Herbicidal 7-chloro-benzothiazolyloxyacetamides BAYER AKTIENGESELLSCHAFT (DE) 1993-08-10 US disclosed
US-5234896-A Herbicidal 7-chloro-benzothiazolyloxyacetamides BAYER AKTIENGESELLSCHAFT (DE) 1993-08-10 US disclosed
EP-0510479-A1 7-Chloro-benzothiazolyloxyacetamide BAYER AG (DE) 1992-10-28 EP disclosed
EP-0510479-A1 7-Chloro-benzothiazolyloxyacetamide BAYER AG (DE) 1992-10-28 EP disclosed
EP-0510479-A1 7-Chloro-benzothiazolyloxyacetamide BAYER AG (DE) 1992-10-28 EP disclosed