Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340443 | 0.82 | ELANE (0.42) | PTGS1PTGS2ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL9565665 | 0.79 | PSMB8 (0.43) | PSMB8PTGS1PTGS2HSP90AA1HSP90AB1 | |
| SCHEMBL9590384 | 0.76 | MEN1 (0.69) | ALDH1A1ALOX5KMT2A | |
| SCHEMBL18026590 | 0.75 | ACACB (0.47) | ACACBKMT2A | |
| SCHEMBL13824618 | 0.75 | PSMB8 (0.51) | PSMB8ALDH1A1L3MBTL1HSP90AA1HSP90AB1 | |
| SCHEMBL11334172 | 0.74 | ALDH1A1 (0.55) | PSMB8PTGS1PTGS2ALDH1A1HSP90AA1 | |
| SCHEMBL9843032 | 0.73 | CYP3A4 (0.39) | ALDH1A1L3MBTL1ALOX5ACACBKMT2A | |
| SCHEMBL6842459 | 0.73 | PTGS1 (0.58) | PTGS1PTGS2L3MBTL1KMT2AF2RL3 | |
| SCHEMBL11347104 | 0.72 | HSD17B10 (0.38) | ALDH1A1ACACBKMT2A | |
| SCHEMBL9585282 | 0.72 | SMN1; SMN2 (0.51) | ALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039440-B1 | MEDICINES CONTAINING SUBSTITUTED BENZOTHIAZOL-2-(3H)-ONES | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| US-4353919-A | Analgesic and antipyretic pharmaceutical compositions containing a benzothiazol-2(3H)-one | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-10-12 | — | — | US | disclosed |
| EP-0039440-A1 | Medicines containing substituted benzothiazol-2-(3H)-ones | Dr. Karl Thomae GmbH (DE) | 1981-11-11 | — | — | EP | disclosed |