SCHEMBL9301532

SCHEMBL9301532

NC(=O)COc1nc2cccc(F)c2s1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
AKR1A1 P14550 1/20 0.38
AKR1B1 P15121 1/20 0.38
PTGS1 P23219 2/20 0.36
PTGS2 P35354 2/20 0.36
ACACA Q13085 1/20 0.36
NAAA Q02083 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
ALDH1A1 P00352 1/20 0.35
KCNN4 O15554 1/20 0.35
SYK P43405 2/20 0.35
KDM4E B2RXH2 4/20 0.35
HTT P42858 2/20 0.35
HSP90AA1 P07900 1/20 0.35
HSP90AB1 P08238 1/20 0.35
LMNA P02545 2/20 0.34
GAA P10253 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9565665 0.83 PSMB8 (0.43) MEN1KMT2AAKR1B1PTGS1PTGS2
SCHEMBL9264877 0.79 MEN1 (0.69) MEN1KMT2AALDH1A1LMNAGAA
SCHEMBL9280327 0.79 GAA (0.49) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL9281180 0.78 KMT2A (0.61) MEN1KMT2APTGS1PTGS2NPC1
SCHEMBL9300710 0.76 MEN1 (0.43) MEN1KMT2APTGS1PTGS2NAAA
SCHEMBL19691127 0.74 DYRK1A (0.43) MEN1KMT2AAKR1A1AKR1B1NAAA
SCHEMBL9077622 0.73 PIM1 (0.38) NPC1RAB9AALDH1A1KCNN4SYK
SCHEMBL9563369 0.70 ACACA (0.38) KMT2AACACAALDH1A1KCNN4SYK
SCHEMBL9551288 0.70 ALDH1A1 (0.49) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL7960065 0.69 AKR1A1 (0.43) MEN1KMT2AAKR1A1AKR1B1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5356864-A New herbicidal fluorobenzothiazolyloxyacetamides BAYER AKTIENGESELLSCHAFT (DE) 1994-10-18 US claimed
EP-0588183-A1 Fluoro benzothiazolyloxyacetamide BAYER AG (DE) 1994-03-23 EP claimed