Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 3/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534331 | 0.83 | KDM1A (0.41) | TRPM5TRPM4SMN1; SMN2GSK3BKDM4E | |
| SCHEMBL12993226 | 0.79 | TRPM5 (0.41) | TRPM5SMN1; SMN2TSHRALDH1A1HSD17B10 | |
| SCHEMBL10534782 | 0.79 | HPGD (0.49) | SMN1; SMN2TSHRALDH1A1HSD17B10GSK3B | |
| SCHEMBL9490322 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2TSHRALDH1A1HSD17B10GSK3B | |
| SCHEMBL10534373 | 0.75 | BCHE (0.35) | SMN1; SMN2ALDH1A1GSK3BKDM4EUSP2 | |
| SCHEMBL9883346 | 0.73 | NPC1 (0.46) | SMN1; SMN2TSHRALDH1A1KDM4EPOLB | |
| SCHEMBL10537698 | 0.72 | VHL (0.47) | SMN1; SMN2TSHRALDH1A1HSD17B10GSK3B | |
| SCHEMBL2056489 | 0.69 | MAPT (0.35) | SMN1; SMN2TSHRKDM4ELMNAPOLB | |
| SCHEMBL13785192 | 0.69 | POLB (0.35) | SMN1; SMN2KDM4EPOLBNPSR1MAPT | |
| SCHEMBL22562168 | 0.68 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRALDH1A1HSD17B10GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526951-A1 | 3-Phenyl benzo b thiophenes as pesticidal compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-02-10 | — | — | EP | disclosed |