Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | MMP1 | P03956 | 5/20 | 0.34 |
| ▸ | MMP2 | P08253 | 5/20 | 0.34 |
| ▸ | MMP9 | P14780 | 5/20 | 0.34 |
| ▸ | MMP8 | P22894 | 5/20 | 0.34 |
| ▸ | MMP13 | P45452 | 5/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1791517 | 1.00 | THRB (0.50) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL497469 | 0.91 | THRB (0.42) | THRBTET2 | |
| SCHEMBL6915704 | 0.82 | THRB (0.39) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL13142417 | 0.80 | TET2 (0.37) | THRBTET2 | |
| SCHEMBL11782533 | 0.79 | THRB (0.43) | THRB | |
| SCHEMBL7269501 | 0.77 | THRB (0.50) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL29098786 | 0.77 | THRB (0.50) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL29098783 | 0.77 | THRB (0.50) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL29098792 | 0.77 | THRB (0.50) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL29098781 | 0.77 | THRB (0.50) | THRBCA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527661-A1 | Metal beta-diketonates | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1993-02-17 | — | — | EP | disclosed |