SCHEMBL497469

SCHEMBL497469

CCC(F)(C(=O)O)C(F)(F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.42
TET2 Q6N021 1/20 0.34
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
FFAR3 O14843 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9565809 0.91 THRB (0.50) THRBTET2
SCHEMBL1791517 0.91 THRB (0.50) THRBTET2
SCHEMBL13142417 0.84 TET2 (0.37) THRBTET2MEN1ALDH1A1CYP1A2
SCHEMBL16285652 0.73 THRB (0.41) THRBMEN1ALDH1A1CYP1A2KMT2A
SCHEMBL1000250 0.72 TET2 (0.50) THRBTET2MEN1ALDH1A1CYP1A2
SCHEMBL1000252 0.72 TET2 (0.50) THRBTET2MEN1ALDH1A1CYP1A2
SCHEMBL29098786 0.71 THRB (0.50) THRB
SCHEMBL29098792 0.71 THRB (0.50) THRB
SCHEMBL29098781 0.71 THRB (0.50) THRB
SCHEMBL7269501 0.71 THRB (0.50) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3446177-B1 FLAME RETARDANCY OF ELECTROCHROMIC DEVICES GENTEX CORP (US) 2024-02-28 EP claimed
US-10459307-B2 Flame retardancy of electrochromic devices GENTEX CORPORATION (US) 2019-10-29 US claimed
WO-2017183004-A1 FLAME RETARDANCY OF ELECTROCHROMIC DEVICES GENTEX CORPORATION (US) 2017-10-26 WO claimed
US-20170307952-A1 FLAME RETARDANCY OF ELECTROCHROMIC DEVICES GENTEX CORPORATION 2017-10-26 US claimed
EP-3446177-B1 FLAME RETARDANCY OF ELECTROCHROMIC DEVICES GENTEX CORP (US) 2024-02-28 EP disclosed
US-20210318613-A9 RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2021-10-14 US disclosed
US-20200393761-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND RESIST PATTERN-FORMING METHOD JSR CORPORATION (JP) 2020-12-17 US disclosed
US-10459307-B2 Flame retardancy of electrochromic devices GENTEX CORPORATION (US) 2019-10-29 US disclosed
WO-2017183004-A1 FLAME RETARDANCY OF ELECTROCHROMIC DEVICES GENTEX CORPORATION (US) 2017-10-26 WO disclosed
US-20170307952-A1 FLAME RETARDANCY OF ELECTROCHROMIC DEVICES GENTEX CORPORATION 2017-10-26 US disclosed
US-8106222-B2 Fluorine-containing ether compound FUJIFILM CORPORATION (JP) 2012-01-31 US disclosed
US-20090018350-A1 NOVEL FLUORINE-CONTAINING ETHER COMPOUND FUJIFILM CORPORATION (JP) 2009-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018350-A1 NOVEL FLUORINE-CONTAINING ETHER COMPOUND AFF4, AFF1, AFF2 THRB 2210/4885TET2 1835/4885MEN1 1829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.