Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10874507 | 0.97 | FDPS (0.39) | FDPSLMNAHSD17B10TSHRSMPD1 | |
| SCHEMBL27802944 | 0.90 | FDPS (0.38) | FDPSLMNAHSD17B10ALDH1A1 | |
| SCHEMBL28190435 | 0.85 | FDPS (0.45) | FDPSTSHRSMPD1ALDH1A1SCN5A | |
| SCHEMBL28190434 | 0.81 | FDPS (0.48) | FDPSTSHRSMPD1ALDH1A1SCN5A | |
| SCHEMBL28189832 | 0.81 | FDPS (0.48) | FDPSTSHRSMPD1ALDH1A1SCN5A | |
| SCHEMBL2334420 | 0.78 | — | — | |
| SCHEMBL27558769 | 0.77 | SMN1; SMN2 (0.41) | FDPSLMNAHSD17B10TSHRSMPD1 | |
| SCHEMBL3915597 | 0.76 | ALDH1A1 (0.40) | FDPSLMNAHSD17B10TSHRALDH1A1 | |
| SCHEMBL11873578 | 0.75 | FDPS (0.37) | FDPSSMPD1ALDH1A1SCN5ASCN9A | |
| SCHEMBL10902351 | 0.74 | FDPS (0.36) | FDPSLMNAHSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564356-A1 | 4-phenylaminomethylimidazole derivatives, process for their preparation, angiotensin II receptor antagonists and their application in therapy | FOURNIER INDUSTRIE ET SANTE (FR) | 1993-10-06 | — | — | EP | disclosed |
| EP-0028940-B1 | ANTIARRHYTHMIC TETRAHYDRONAPHTHALENE DERIVATIVES | E.R. Squibb & Sons, Inc. (US) | 1983-09-07 | — | — | EP | disclosed |
| US-4350812-A | Antiarrhythmic tetrahydronaphthalene derivatives | E. R. SQUIBB & SONS, INC. (US) | 1982-09-21 | — | — | US | disclosed |
| US-4302453-A | Antiarrhythmic tetrahydronaphthalene derivatives | E. R. SQUIBB & SONS, INC. (US) | 1981-11-24 | — | — | US | disclosed |
| EP-0028940-A1 | Antiarrhythmic tetrahydronaphthalene derivatives | E.R. Squibb & Sons, Inc. (US) | 1981-05-20 | — | — | EP | disclosed |