SCHEMBL9566024

SCHEMBL9566024

C=CCON(C)C(=O)NN=C(c1ccc(Cl)cc1)c1ccc(OS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
ALDH1A1 P00352 1/20 0.34
CYP11B1 P15538 3/20 0.34
CYP11B2 P19099 3/20 0.34
ENPP3 O14638 1/20 0.34
ENPP1 P22413 1/20 0.34
ENPP2 Q13822 1/20 0.34
LSS P48449 1/20 0.33
LMNA P02545 2/20 0.33
CXCR2 P25025 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA9 Q16790 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9416661 0.85 RAB9A (0.42) MEN1KMT2AALDH1A1CYP11B1CYP11B2
SCHEMBL9079609 0.78 MEN1 (0.42) MEN1KMT2AALDH1A1ENPP3ENPP1
SCHEMBL10973313 0.78 MEN1 (0.42) MEN1KMT2AALDH1A1ENPP3ENPP1
SCHEMBL11032658 0.78 MEN1 (0.41) MEN1KMT2AALDH1A1ENPP3ENPP1
SCHEMBL11032656 0.78 MEN1 (0.41) MEN1KMT2AALDH1A1ENPP3ENPP1
SCHEMBL8535057 0.76 ALDH1A1 (0.53) MEN1KMT2AALDH1A1ENPP3ENPP1
SCHEMBL9566010 0.76 ALDH1A1 (0.35) MEN1KMT2AALDH1A1CYP11B1CYP11B2
SCHEMBL7104414 0.76 ENPP1 (0.41) MEN1KMT2AALDH1A1ENPP3ENPP1
SCHEMBL7104412 0.76 ENPP1 (0.41) MEN1KMT2AALDH1A1ENPP3ENPP1
SCHEMBL9079636 0.76 SMN1; SMN2 (0.44) MEN1KMT2AALDH1A1ENPP3ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0566534-A1 Derivatives of benzophenone CIBA-GEIGY AG (CH) 1993-10-20 EP disclosed