Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.81 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.78 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565903 | 0.94 | AGTR1 (0.82) | AGTR1PTGER4PTGER3 | |
| SCHEMBL9566143 | 0.92 | AGTR1 (0.82) | AGTR1 | |
| SCHEMBL9565945 | 0.90 | AGTR1 (0.82) | AGTR1 | |
| SCHEMBL9566049 | 0.90 | AGTR1 (0.82) | AGTR1PTGER4PTGER3 | |
| SCHEMBL9565941 | 0.89 | AGTR1 (0.86) | AGTR1PTGER4PTGER3 | |
| L-159913 SCHEMBL9144158 | 0.89 | AGTR1 (1.00) | AGTR1 | |
| SCHEMBL9566157 | 0.89 | AGTR1 (0.78) | AGTR1PTGER4PTGER3 | |
| SCHEMBL9565990 | 0.88 | AGTR1 (0.84) | AGTR1PTGER4PTGER3 | |
| SCHEMBL9149031 | 0.88 | AGTR1 (0.84) | AGTR1 | |
| SCHEMBL9144443 | 0.88 | AGTR1 (0.84) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526001-A1 | Substituted triazolinones | MERCK & CO. INC. (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1993001177-A1 | SUBSTITUTED TRIAZOLINONES | MERCK & CO., INC. (US) | 1993-01-21 | — | — | WO | disclosed |