SCHEMBL9566112

SCHEMBL9566112

CCn1c2ccccc2c2ccc(C=NN(c3ccccc3)c3ccccc3)cc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.55
POLB P06746 4/20 0.55
HTT P42858 3/20 0.55
PKM P14618 1/20 0.55
SRC P12931 4/20 0.53
ALDH1A1 P00352 9/20 0.53
HPGD P15428 8/20 0.53
SMN1; SMN2 Q16637 7/20 0.53
MAPT P10636 7/20 0.53
LMNA P02545 5/20 0.53
HSD17B10 Q99714 2/20 0.53
USP2 O75604 1/20 0.53
TSHR P16473 1/20 0.53
CASP1 P29466 1/20 0.53
MEN1 O00255 8/20 0.48
KMT2A Q03164 8/20 0.48
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29709939 0.92 KDM4E (0.66) KDM4EPOLBHTTPKMSRC
SCHEMBL170206 0.92 KDM4E (0.66) KDM4EPOLBHTTPKMSRC
SCHEMBL332438 0.92 KDM4E (0.66) KDM4EPOLBHTTPKMSRC
SCHEMBL14196891 0.87 KDM4E (0.59) KDM4EPOLBHTTPKMSRC
SCHEMBL15892554 0.83 KMT2A (0.48) KDM4EPOLBALDH1A1HPGDMAPT
SCHEMBL9192246 0.82 KDM4E (0.53) KDM4EPOLBHTTPKMSRC
SCHEMBL13329109 0.82 KDM4E (0.53) KDM4EPOLBHTTPKMSRC
SCHEMBL14196895 0.82 ALDH1A1 (0.57) KDM4EPOLBHTTPKMSRC
SCHEMBL11132062 0.81 PTGER4 (0.57) KDM4EPOLBHTTPKMSRC
SCHEMBL1596345 0.81 KDM4E (0.64) KDM4EPOLBHTTPKMSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1788037-B1 Titanylphthalocyanin crystal, method for preparing the same, and electrophotographic photoreceptor KYOCERA MITA CORP (JP) 2013-01-02 EP disclosed
US-7855286-B2 Titanyl phthalocyanin crystal, method for preparing the same and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2010-12-21 US disclosed
US-7855286-B2 Titanyl phthalocyanin crystal, method for preparing the same and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2010-12-21 US disclosed
US-20100081073-A1 Titanyl phthalocyanin crystal, method for preparing the same and electrophotographic photoconductor KYOCERA MITA CORPORATION 2010-04-01 US disclosed
US-20100081073-A1 Titanyl phthalocyanin crystal, method for preparing the same and electrophotographic photoconductor KYOCERA MITA CORPORATION 2010-04-01 US disclosed
EP-1093025-B1 Titanyl phthalocyanine crystal and production method of the same and electrophotosensitive material KYOCERA MITA CORP (JP) 2007-01-31 EP disclosed
EP-0546994-A1 Method for optical information-storage CIBA-GEIGY AG (CH) 1993-06-16 EP disclosed