Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.30 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25881226 | 0.83 | CNR1 (0.36) | TBXAS1PTGER4PTGER3AKT1KDM4E | |
| SCHEMBL13305489 | 0.81 | TBXAS1 (0.44) | TBXAS1TBXA2RPTGER4PTGER3AKT1 | |
| SCHEMBL10406426 | 0.78 | TBXA2R (0.52) | TBXAS1TBXA2RPTGER4PTGER3KDM4E | |
| SCHEMBL9566225 | 0.77 | TBXAS1 (0.47) | TBXAS1TBXA2RPTGER4AKT1 | |
| SCHEMBL8701332 | 0.74 | TBXA2R (0.34) | TBXAS1TBXA2R | |
| SCHEMBL8701326 | 0.74 | TBXA2R (0.34) | TBXAS1TBXA2R | |
| SCHEMBL8701328 | 0.74 | TBXA2R (0.34) | TBXAS1TBXA2R | |
| SCHEMBL25881230 | 0.72 | AKT1 (0.33) | TBXAS1PTGER4PTGER3AKT1KDM4E | |
| SCHEMBL25881227 | 0.70 | AKT1 (0.32) | TBXAS1PTGER4PTGER3AKT1 | |
| SCHEMBL10405680 | 0.70 | ALDH1A1 (0.38) | TBXA2RPTGER4PTGER3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536713-A1 | Oxazole and imidazole derivatives as prostaglandin analogs | E.R. SQUIBB & SONS, INC. (US) | 1993-04-14 | — | — | EP | disclosed |