Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566213 | 0.84 | TBXA2R (0.43) | TBXA2RFFAR1PTGER1PTGER4PTGER3 | |
| SCHEMBL9566289 | 0.81 | TBXA2R (0.42) | TBXA2RFFAR1PTGER1PTGER4PTGER3 | |
| SCHEMBL9566135 | 0.79 | CYP4F2 (0.53) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3728799 | 0.76 | CYP4F2 (0.58) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL59198 | 0.76 | KEAP1 (0.65) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL9566280 | 0.74 | TBXA2R (0.38) | TBXA2RFFAR1PTGER1PTGER4PTGER3 | |
| SCHEMBL27458277 | 0.73 | KEAP1 (0.63) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8573204 | 0.73 | KEAP1 (0.56) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL11633504 | 0.70 | FFAR1 (0.51) | TBXA2RFFAR1KEAP1FFAR4 | |
| SCHEMBL9173189 | 0.70 | FFAR1 (0.53) | FFAR1PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827868-A | Prostaglandin analogs | E. R. SQUIBB & SONS, INC. (US) | 1998-10-27 | — | — | US | disclosed |
| EP-0536713-A1 | Oxazole and imidazole derivatives as prostaglandin analogs | E.R. SQUIBB & SONS, INC. (US) | 1993-04-14 | — | — | EP | disclosed |