Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9566348

CSc1cc(C)c(N)c(SC)c1N.N.N

nearest known ligand 0.37

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Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364269 0.98 ALDH1A1 (0.39) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL48465 0.98 ALDH1A1 (0.39) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL5837930 0.90 ALDH1A1 (0.33) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL9180441 0.84 ALDH1A1 (0.46) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL9578834 0.84
SCHEMBL15256900 0.83 ALDH1A1 (0.32) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL9722894 0.82 NPC1 (0.38) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL8764612 0.82
SCHEMBL6911477 0.80 ALDH1A1 (0.32) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL8764562 0.80 ALDH1A1 (0.32) ALDH1A1TP53CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0570798-A1 Use of alkylthio-substituted aromatic diamines as a curing agent for polyisocyanates in coating compositions or jointing compounds BAYER AG (DE) 1993-11-24 EP claimed
EP-0228190-B1 RIM POLYURETHANES COMPRISING MIXED DIAMINE CHAIN EXTENDERS AND PROCESS AND COMPOSITION FOR THEIR PRODUCTION ETHYL CORPORATION (US) 1991-02-27 EP claimed