Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764612 | 0.93 | — | — | |
| SCHEMBL1797285 | 0.92 | — | — | |
| SCHEMBL48603 | 0.89 | ALDH1A1 (0.34) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL8764562 | 0.85 | ALDH1A1 (0.32) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL9184128 | 0.84 | ALDH1A1 (0.40) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL5522764 | 0.84 | ALDH1A1 (0.33) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL29364269 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL48465 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| Ammonia Solution, Strong SCHEMBL9566348 | 0.80 | ALDH1A1 (0.37) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL5837930 | 0.79 | ALDH1A1 (0.33) | ALDH1A1TP53CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265940-B1 | AROMATIC AMINE CURATIVES AND THEIR USE | ALBERMARLE CORP (US) | 2004-10-27 | — | — | EP | disclosed |
| US-6509434-B1 | Condensation polymerization of alkylthiated mononuclear aromatic amines and isocyanate prepolymer to produce polyurethanes, polyureaurethanes and/or polyureas | ALBEMARLE CORPORATION | 2003-01-21 | — | — | US | disclosed |
| EP-1265940-A2 | AROMATIC AMINE CURATIVES AND THEIR USE | Albermarle Corporation (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070841-A2 | AROMATIC AMINE CURATIVES AND THEIR USE | ALBEMARLE CORPORATION (US) | 2001-09-27 | — | — | WO | disclosed |