Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | AGPAT2 | O15120 | 12/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4366486 | 0.85 | AGPAT2 (1.00) | RECQLALDH1A1AGPAT2MEN1LMNA | |
| SCHEMBL4279053 | 0.83 | RECQL (0.60) | RECQLALDH1A1AGPAT2MEN1LMNA | |
| SCHEMBL4281666 | 0.83 | AGPAT2 (0.67) | RECQLALDH1A1AGPAT2MEN1LMNA | |
| SCHEMBL9566545 | 0.82 | RECQL (0.56) | RECQLALDH1A1AGPAT2MEN1LMNA | |
| SCHEMBL2622384 | 0.82 | AGPAT2 (0.88) | RECQLALDH1A1AGPAT2MEN1LMNA | |
| SCHEMBL2622388 | 0.82 | AGPAT2 (0.88) | RECQLALDH1A1AGPAT2MEN1LMNA | |
| SCHEMBL4358716 | 0.81 | AGPAT2 (0.82) | RECQLALDH1A1AGPAT2MEN1LMNA | |
| SCHEMBL4362545 | 0.81 | AGPAT2 (0.86) | RECQLALDH1A1AGPAT2MEN1LMNA | |
| SCHEMBL13622456 | 0.81 | AGPAT2 (0.86) | RECQLALDH1A1AGPAT2MEN1LMNA | |
| SCHEMBL9566435 | 0.80 | MGAM (0.54) | RECQLALDH1A1AGPAT2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |