Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566569 | 0.82 | DHFR (0.44) | NPC1TSHRRAB9ARECQLPOLB | |
| SCHEMBL9566471 | 0.80 | RECQL (0.78) | RECQLALDH1A1AGPAT2LMNAMEN1 | |
| SCHEMBL14125145 | 0.78 | GAA (0.56) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL3952206 | 0.77 | HSP90AA1 (0.68) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL9566518 | 0.77 | NPC1 (0.47) | NPC1RAB9AALDH1A1POLBAGPAT2 | |
| SCHEMBL16179144 | 0.77 | GPR35 (0.54) | NPC1RAB9AALDH1A1AGPAT2HTT | |
| SCHEMBL6668063 | 0.76 | NPC1 (0.55) | NPC1RECQLALDH1A1AGPAT2LMNA | |
| SCHEMBL4786950 | 0.76 | MGAM (0.47) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL30031048 | 0.76 | SLC2A1 (0.45) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL30957326 | 0.76 | NPC1 (0.56) | MGAMGAASIMGAM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4103009-A | ANTIULCER AGENTS, DIURETICS | NIPPON SHINYAKU CO., LTD. (JP) | 1978-07-25 | — | — | US | claimed |
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-4873242-A | NOOTROPIC AGENTS | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-10 | — | — | US | disclosed |
| US-4103009-A | ANTIULCER AGENTS, DIURETICS | NIPPON SHINYAKU CO., LTD. (JP) | 1978-07-25 | — | — | US | disclosed |