Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | AGPAT2 | O15120 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4357076 | 0.87 | AGPAT2 (0.78) | RECQLAGPAT2ALDH1A1LMNAMEN1 | |
| SCHEMBL9566538 | 0.84 | AGPAT2 (0.51) | RECQLAGPAT2ALDH1A1LMNAMEN1 | |
| SCHEMBL9566569 | 0.83 | DHFR (0.44) | RECQLAGPAT2DHFRNPC1RAB9A | |
| SCHEMBL9566471 | 0.82 | RECQL (0.78) | RECQLAGPAT2ALDH1A1LMNAMEN1 | |
| SCHEMBL11612156 | 0.80 | KDM4E (0.50) | ALDH1A1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL360551 | 0.76 | HTR2C (0.52) | ALDH1A1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL29684402 | 0.76 | HTR2C (0.52) | ALDH1A1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL4363416 | 0.75 | AGPAT2 (0.83) | RECQLAGPAT2ALDH1A1LMNAMEN1 | |
| SCHEMBL14345658 | 0.73 | HTR2C (0.52) | ALDH1A1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL15716191 | 0.72 | HTR2C (0.49) | ALDH1A1LMNAMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |