Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30706658 | 0.80 | POLB (0.42) | OPRM1SLC6A4POLBATMOPRD1 | |
| SCHEMBL24094554 | 0.75 | OPRM1 (0.47) | OPRM1SLC6A4SLC6A2SLC6A3POLB | |
| SCHEMBL15760245 | 0.74 | OPRM1 (0.46) | OPRM1SLC6A4SLC6A2SLC6A3POLB | |
| Hydrochloric Acid SCHEMBL28893436 | 0.73 | OPRM1 (0.43) | OPRM1SLC6A4SLC6A2SLC6A3POLB | |
| Hydrochloric Acid SCHEMBL15416341 | 0.72 | POLB (0.44) | OPRM1SLC6A4SLC6A2SLC6A3POLB | |
| SCHEMBL13118615 | 0.72 | OPRM1 (0.45) | OPRM1SLC6A4SLC6A2SLC6A3POLB | |
| SCHEMBL30707055 | 0.72 | OPRM1 (0.39) | OPRM1SLC6A4POLBOPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL17535049 | 0.72 | OPRM1 (0.51) | OPRM1SLC6A4SLC6A2SLC6A3POLB | |
| Hydrochloric Acid SCHEMBL1282401 | 0.72 | OPRM1 (0.51) | OPRM1SLC6A4SLC6A2SLC6A3POLB | |
| SCHEMBL11581057 | 0.71 | ALOX15 (0.48) | OPRM1SLC6A4POLBATMOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550025-A1 | Azaspiroheptanes and octanes and processes for their production | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | claimed |
| EP-0550025-A1 | Azaspiroheptanes and octanes and processes for their production | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-07-07 | — | — | EP | disclosed |