Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 8/20 | 0.60 |
| ▸ | HBB | P68871 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | EDNRA | P25101 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLG | P54098 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053218 | 0.88 | MEN1 (0.57) | PNPHBBTSHRBLMUSP2 | |
| SCHEMBL10861011 | 0.85 | PNP (0.62) | PNPHBBTSHRBLMUSP2 | |
| SCHEMBL13733434 | 0.80 | PNP (0.59) | PNPHBBTSHRBLMUSP2 | |
| Acyclovir SCHEMBL8651162 | 0.78 | PNP (0.88) | PNPHBBTSHRBLMUSP2 | |
| SCHEMBL7200355 | 0.76 | ALDH1A1 (0.42) | PNPHBBTSHRBLMUSP2 | |
| Acyclovir SCHEMBL16061503 | 0.76 | PNP (0.95) | PNPHBBTSHRBLMUSP2 | |
| Acyclovir SCHEMBL3175 | 0.75 | PNP (1.00) | PNPHBBTSHRBLMUSP2 | |
| Acyclovir SCHEMBL2269160 | 0.75 | PNP (1.00) | PNPHBBTSHRBLMUSP2 | |
| Acyclovir SCHEMBL3664893 | 0.75 | PNP (1.00) | PNPHBBTSHRBLMUSP2 | |
| Acyclovir SCHEMBL9479083 | 0.75 | PNP (0.93) | PNPHBBTSHRBLMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564006-A2 | Process for preparing purine derivatives and novel purine derivatives | KRKA, tovarna zdravil, n.sol.o (YU) | 1993-10-06 | — | — | EP | claimed |
| EP-0289992-A2 | Process for preparing purine derivates | KEMIJSKI INSTITUT (SI) | 1988-11-09 | — | — | EP | claimed |
| EP-0564006-A2 | Process for preparing purine derivatives and novel purine derivatives | KRKA, tovarna zdravil, n.sol.o (YU) | 1993-10-06 | — | — | EP | disclosed |
| EP-0564006-A2 | Process for preparing purine derivatives and novel purine derivatives | KRKA, tovarna zdravil, n.sol.o (YU) | 1993-10-06 | — | — | EP | disclosed |
| EP-0289992-A2 | Process for preparing purine derivates | KEMIJSKI INSTITUT (SI) | 1988-11-09 | — | — | EP | disclosed |