Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582217 | 0.94 | GAA (0.48) | SMN1; SMN2GAAABCB1LMNAMAPT | |
| SCHEMBL12871748 | 0.85 | GAA (0.43) | SMN1; SMN2GAAABCB1LMNAMAPT | |
| SCHEMBL4580348 | 0.80 | ABCB1 (0.48) | GAAABCB1LMNAHTTMEN1 | |
| SCHEMBL11341597 | 0.78 | CYP3A4 (0.55) | SMN1; SMN2CYP3A4GAALMNAMAPT | |
| SCHEMBL4579151 | 0.74 | MAPT (0.47) | SMN1; SMN2GAALMNAMAPTHTT | |
| SCHEMBL9566636 | 0.74 | ALDH1A1 (0.41) | SMN1; SMN2CYP3A4LMNAMAPTHTT | |
| SCHEMBL30732620 | 0.73 | ABCB1 (0.46) | GAAABCB1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL30732527 | 0.72 | ABCB1 (0.54) | GAAABCB1MAPTHTTKMT2A | |
| SCHEMBL4615298 | 0.72 | ABCB1 (0.43) | SMN1; SMN2GAAABCB1LMNAMAPT | |
| SCHEMBL11224199 | 0.72 | GAA (0.42) | SMN1; SMN2GAAABCB1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543482-A1 | Aminocarboxylate ligands having substituted aromatic amide moieties | BRACCO INTERNATIONAL B.V. (NL) | 1993-05-26 | — | — | EP | disclosed |