Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28227271 | 0.79 | AR (0.39) | ALDH1A1LMNAMAPTHTTCYP3A4 | |
| SCHEMBL9566637 | 0.74 | SMN1; SMN2 (0.45) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL11666008 | 0.72 | AR (0.57) | ALDH1A1MAPTKMT2APOLBPKM | |
| SCHEMBL28222617 | 0.72 | AR (0.36) | AR | |
| SCHEMBL4582217 | 0.71 | GAA (0.48) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL28979175 | 0.71 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2MITFMAPT | |
| SCHEMBL7986009 | 0.70 | TDP1 (0.36) | AR | |
| SCHEMBL14515256 | 0.69 | MAPT (0.53) | ALDH1A1MAPTKMT2AAR | |
| SCHEMBL14515262 | 0.69 | MAPT (0.53) | ALDH1A1MAPTKMT2AAR | |
| SCHEMBL11665934 | 0.69 | MAPT (0.53) | ALDH1A1MAPTKMT2AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543482-A1 | Aminocarboxylate ligands having substituted aromatic amide moieties | BRACCO INTERNATIONAL B.V. (NL) | 1993-05-26 | — | — | EP | disclosed |