Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566694 | 0.88 | GRIN2D (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9566707 | 0.86 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1202914 | 0.83 | SMN1; SMN2 (0.47) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9566685 | 0.82 | TSHR (0.39) | SMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9566659 | 0.81 | MEN1 (0.32) | TSHRL3MBTL1MEN1ALDH1A1GAA | |
| SCHEMBL9566665 | 0.80 | TSHR (0.34) | SMN1; SMN2TSHR | |
| SCHEMBL8464048 | 0.80 | METAP2 (0.39) | METAP2SMN1; SMN2PKMMAPTPOLB | |
| SCHEMBL9566708 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2PKMMAPTTDP1L3MBTL1 | |
| SCHEMBL9566641 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2PKMPOLBTDP1L3MBTL1 | |
| SCHEMBL27830419 | 0.78 | THRB (0.41) | METAP2SMN1; SMN2PKMMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545866-A1 | Process for the preparation of trifluorobenzol derivatives | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | claimed |
| EP-0545866-A1 | Process for the preparation of trifluorobenzol derivatives | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |