Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.52 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.52 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.52 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.52 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566778 | 0.85 | P4HTM (0.61) | P4HTMNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9566835 | 0.83 | P4HTM (0.63) | P4HTMNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9566802 | 0.83 | NPC1 (0.67) | P4HTMNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9566795 | 0.83 | P4HTM (0.59) | P4HTMNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12020444 | 0.83 | P4HTM (0.62) | P4HTMNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9566807 | 0.83 | P4HTM (0.59) | P4HTMNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9566789 | 0.81 | P4HTM (0.60) | P4HTMNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9566888 | 0.81 | P4HTM (0.57) | P4HTMNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3645995 | 0.81 | P4HTM (0.70) | P4HTMNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9566901 | 0.81 | KMT2A (0.62) | SMN1; SMN2MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |