Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.51 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519528 | 0.88 | RAB9A (0.58) | NPC1RAB9AKDM4EALDH1A1P4HTM | |
| SCHEMBL9537850 | 0.86 | ALDH1A1 (0.69) | NPC1RAB9AKDM4EALDH1A1P4HTM | |
| SCHEMBL9566833 | 0.85 | P4HTM (0.63) | ALDH1A1P4HTMPTPN1CXCR2CXCR1 | |
| SCHEMBL9566835 | 0.85 | P4HTM (0.63) | NPC1RAB9AKDM4EALDH1A1P4HTM | |
| SCHEMBL9566797 | 0.83 | P4HTM (0.67) | NPC1RAB9AALDH1A1P4HTMHDAC6 | |
| SCHEMBL9517987 | 0.83 | P4HTM (0.55) | ALDH1A1P4HTMMEN1KMT2AHPGD | |
| SCHEMBL12020439 | 0.82 | RAB9A (0.66) | NPC1RAB9AKDM4EALDH1A1P4HTM | |
| SCHEMBL9566760 | 0.82 | RAB9A (0.60) | NPC1RAB9AKDM4EALDH1A1P4HTM | |
| SCHEMBL9566803 | 0.81 | P4HTM (0.66) | NPC1RAB9AKDM4EALDH1A1P4HTM | |
| SCHEMBL9566776 | 0.81 | P4HTM (0.66) | NPC1RAB9AKDM4EALDH1A1P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |