Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | LCK | P06239 | 4/20 | 0.53 |
| ▸ | KIT | P10721 | 3/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566781 | 0.86 | MEN1 (0.61) | KMT2AMEN1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL9566801 | 0.84 | MAPT (0.56) | KMT2AMEN1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL12020926 | 0.84 | MAPT (0.56) | KMT2AMEN1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL9566838 | 0.84 | MAPT (0.56) | KMT2AMEN1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL9566839 | 0.83 | MEN1 (0.57) | KMT2AMEN1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL9566885 | 0.82 | MAPT (0.54) | KMT2AMEN1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL9566750 | 0.82 | MEN1 (0.54) | KMT2AMEN1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL13550090 | 0.82 | KMT2A (0.69) | KMT2AMEN1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL24141032 | 0.81 | MAPT (0.84) | KMT2AMEN1TSHRMAPTKCNK3 | |
| SCHEMBL9566797 | 0.81 | P4HTM (0.67) | KMT2AMEN1MAPTSMN1; SMN2KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |