Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.53 |
| ▸ | KIT | P10721 | 7/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.52 |
| ▸ | KDR | P35968 | 6/20 | 0.52 |
| ▸ | LCK | P06239 | 4/20 | 0.51 |
| ▸ | CSF1R | P07333 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | TEK | Q02763 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566885 | 0.90 | MAPT (0.54) | MAPTMEN1TSHRKMT2AKDM4E | |
| SCHEMBL9566781 | 0.89 | MEN1 (0.61) | MAPTMEN1TSHRKMT2AKDM4E | |
| SCHEMBL9566839 | 0.88 | MEN1 (0.57) | MAPTMEN1TSHRKMT2AKDM4E | |
| SCHEMBL9566801 | 0.87 | MAPT (0.56) | MAPTMEN1TSHRKMT2AKDM4E | |
| SCHEMBL12020926 | 0.85 | MAPT (0.56) | MAPTMEN1TSHRKMT2AKDM4E | |
| SCHEMBL9566901 | 0.84 | KMT2A (0.62) | MAPTMEN1TSHRKMT2AKDM4E | |
| SCHEMBL9566807 | 0.84 | P4HTM (0.59) | MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9566750 | 0.83 | MEN1 (0.54) | MAPTMEN1TSHRKMT2AKDM4E | |
| SCHEMBL9566758 | 0.83 | NPC1 (0.57) | MEN1KMT2AKDM4ESMN1; SMN2RXFP1 | |
| SCHEMBL9566814 | 0.80 | P4HTM (0.47) | MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |