Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10738156 | 0.84 | CYP3A4 (0.50) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL14138399 | 0.84 | ALDH1A1 (0.52) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL31159576 | 0.82 | CYP3A4 (0.48) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL356846 | 0.80 | TSHR (0.40) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL9566859 | 0.79 | CYP3A4 (0.50) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL30006601 | 0.77 | CYP3A4 (0.38) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL30761055 | 0.74 | ALDH1A1 (0.52) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL3347824 | 0.74 | ALDH1A1 (0.52) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL532944 | 0.74 | ALDH1A1 (0.43) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL30439061 | 0.74 | ALDH1A1 (0.43) | CYP3A4TSHRMAPK1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558857-A1 | Method for the manufacture of P-bromodimethyl aniline | IMI (TAMI) INSTITUTE FOR RESEARCH & DEVELOPMENT LTD. (IL) | 1993-09-08 | — | — | EP | disclosed |