SCHEMBL356846

SCHEMBL356846

Cc1cc(C)c(Br)c(C)c1Br

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
DRD3 P35462 1/20 0.36
CYP1A2 P05177 2/20 0.36
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 4/20 0.32
HSD17B10 Q99714 2/20 0.32
ALOX15 P16050 1/20 0.32
CASP7 P55210 1/20 0.32
HIF1A Q16665 1/20 0.32
ESR2 Q92731 1/20 0.32
POLB P06746 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30006601 0.97 CYP3A4 (0.38) TSHRCYP3A4MAPK1DRD3CYP1A2
SCHEMBL8909014 0.87 CYP1A2 (0.38) TSHRCYP3A4MAPK1DRD3CYP1A2
SCHEMBL9376593 0.84 APEX1 (0.38) TSHRDRD3CYP1A2PDE3BPDE3A
SCHEMBL21218742 0.80 CYP1A2 (0.43) TSHRCYP3A4MAPK1DRD3CYP1A2
SCHEMBL23249000 0.80 CYP3A4 (0.32) TSHRCYP3A4MAPK1DRD3CYP1A2
SCHEMBL13429870 0.80 CYP3A4 (0.32) TSHRCYP3A4MAPK1DRD3CYP1A2
SCHEMBL18061824 0.80 CYP3A4 (0.32) TSHRCYP3A4MAPK1DRD3CYP1A2
SCHEMBL9566864 0.80 CYP3A4 (0.50) TSHRCYP3A4MAPK1CYP1A2LMNA
SCHEMBL7456448 0.80 CYP3A4 (0.40) TSHRCYP3A4MAPK1DRD3CYP1A2
SCHEMBL6379025 0.80 CYP3A4 (0.32) TSHRCYP3A4MAPK1DRD3CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108678731-A Biochemical marker method for fine and close oil-gas reservoir reservoir fracturing improvement effect assessment 国家地质实验测试中心 2018-10-19 CN claimed
US-20160230550-A1 METHOD OF TRACING FLOW OF HYDROCARBON FROM A SUBTERRANEAN RESERVOIR JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2016-08-11 US claimed
US-9284833-B2 Method of tracing flow of hydrocarbon from a subterranean reservoir JOHNSON MATTHEY PLC (GB) 2016-03-15 US claimed
US-20140174730-A1 METHOD OF TRACING FLOW OF HYDROCARBON FROM A SUBTERRANEAN RESERVOIR JOHNSON MATTHEY PLC (GB) 2014-06-26 US claimed
US-8640773-B2 Method of tracing flow of hydrocarbon from a subterranean reservoir JOHNSON MATTHEY PLC (GB) 2014-02-04 US claimed
US-20130277048-A1 METHOD OF TRACING FLOW OF HYDROCARBON FROM A SUBTERRANEAN RESERVOIR TRACERCO LIMITED (GB) 2013-10-24 US claimed
US-20130087329-A1 METHOD OF TRACING FLOW OF HYDROCARBON FROM A SUBTERRANEAN RESERVOIR JOHNSON MATHEY PLC (GB) 2013-04-11 US claimed
US-20260076091-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2026-03-12 US disclosed
US-12295370-B2 Plant health compositions comprising a water-soluble pesticide and a water-insoluble agrochemical MONSANTO TECHNOLOGY LLC (US) 2025-05-13 US disclosed
US-20230276806-A1 Plant Health Compositions Comprising a Water-Soluble Pesticide and a Water-Insoluble Agrochemical MONSANTO TECHNOLOGY LLC (US) 2023-09-07 US disclosed
US-11700853-B2 Plant health compositions comprising a water-soluble pesticide and a water-insoluble agrochemical MONSANTO TECHNOLOGY LLC (US) 2023-07-18 US disclosed
EP-3289041-B1 METHODS USING A SUSTAINED RELEASE SYSTEM FOR RESERVOIR TREATMENT AND MONITORING JOHNSON MATTHEY PLC (GB) 2023-03-08 EP disclosed
WO-2022269218-A1 ACID-RELEASABLE TRACER COMPOSITIONS & METHODS OF MONITORING ACID STIMULATION OF A WELL JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2022-12-29 WO disclosed
US-6210863-B1 ORTHO-SUBSTITUTED ON AT LEAST TWO ARYL RADICALS, ADDITION POLYMERIZATION CIBA SPECIALTY CHEMICALS CORPORATION 2001-04-03 US disclosed
US-6057078-A PHOTOGRAPHY CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-05-02 US disclosed
US-5952152-A POLYMERIZABLE MIXTURE COMPRISING AT LEAST ONE ETHYLENICALLY UNSATURATED COMPOUND AND AN ANIONIC BORON COMPOUND ACTIVATOR CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-09-14 US disclosed
US-5807905-A POLYMERIZATION OF UNSATURATED COMPOUNDS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-15 US disclosed
EP-0520235-B1 Method of preparing 2-bromo-4,6-dinitromesitylene DU PONT (US) 1995-03-29 EP disclosed
EP-0520235-A2 Method of preparing 2-bromo-4,6-dinitromesitylene E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-30 EP disclosed
US-5118880-A Mixing fuming sulfuric acid with bromomesitylene, then concentrated nitric acid E. I. DU PONT DE NEMOURS & CO. (US) 1992-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276806-A1 Plant Health Compositions Comprising a Water-Soluble Pesticide and a Water-Insoluble Agrochemical DNPH1, HDHD5, GGH TSHR 3691/4885CYP3A4 584/4885MAPK1 4368/4885
US-12295370-B2 Plant health compositions comprising a water-soluble pesticide and a water-insoluble agrochemical DNPH1, HDHD5, GGH TSHR 3691/4885CYP3A4 584/4885MAPK1 4368/4885
US-20260076091-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND CRY1, CHRM1, H1-0 TSHR 1177/4885CYP3A4 1704/4885MAPK1 918/4885
US-11700853-B2 Plant health compositions comprising a water-soluble pesticide and a water-insoluble agrochemical DNPH1, HDHD5, GGH TSHR 3691/4885CYP3A4 584/4885MAPK1 4368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.