Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566842 | 0.89 | SENP7 (0.53) | P4HTMRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9566856 | 0.88 | P4HTM (0.60) | P4HTMRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9566783 | 0.87 | RAB9A (0.63) | P4HTMRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9566763 | 0.87 | AHR (0.69) | P4HTMRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9566827 | 0.86 | P4HTM (0.57) | P4HTMRAB9ANPC1MEN1KMT2A | |
| SCHEMBL12020358 | 0.84 | RAB9A (0.66) | P4HTMRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9566737 | 0.83 | NPC1 (0.57) | P4HTMRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9566831 | 0.82 | P4HTM (0.65) | P4HTMRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9566868 | 0.81 | CXCR2 (0.60) | P4HTMRAB9ANPC1ALDH1A1 | |
| SCHEMBL12020466 | 0.77 | NPC1 (0.56) | P4HTMRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |