SCHEMBL9566977

COOC([C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C)C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	DUT	P33316	5/20	0.41

▸	TDP1	Q9NUW8	2/20	0.36

▸	SLC28A1	O00337	1/20	0.33

▸	SLC28A2	O43868	1/20	0.33

▸	SLC29A1	Q99808	1/20	0.33

▸	SLC28A3	Q9HAS3	1/20	0.33

▸	DPAGT1	Q9H3H5	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7524816	0.83	SLC28A1 (0.47)	SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL23710668	0.80	DUT (0.46)	DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL24772633	0.80	DUT (0.46)	DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL21231206	0.78	DUT (0.44)	DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL20820789	0.78	DUT (0.44)	DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL19379558	0.78	DUT (0.44)	DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL23253969	0.78	DUT (0.44)	DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL23253968	0.78	DUT (0.44)	DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL21231208	0.78	DUT (0.44)	DUTTDP1SLC28A1SLC28A2SLC29A1
SCHEMBL19379550	0.78	DUT (0.44)	DUTTDP1SLC28A1SLC28A2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0571087-A1	Cleavable phosphoramidites	ROHM AND HAAS COMPANY (US)	1993-11-24	—	—	EP	disclosed