Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.54 |
| ▸ | CES2 | O00748 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1549080 | 0.85 | CES1 (0.62) | CES1CES2LMNACA2CA4 | |
| Hydrochloric Acid SCHEMBL29089395 | 0.83 | CES1 (0.60) | CES1CES2LMNACA2CA4 | |
| SCHEMBL6663155 | 0.81 | CES2 (0.58) | CES1CES2LMNACA2CA4 | |
| SCHEMBL2171281 | 0.78 | CA12 (0.48) | CES1CES2LMNACA2CA4 | |
| SCHEMBL3948669 | 0.78 | CA12 (0.48) | CES1CES2LMNACA2CA4 | |
| SCHEMBL8445181 | 0.78 | CES1 (0.60) | CES1CES2LMNACA2CA4 | |
| SCHEMBL11213788 | 0.77 | CES2 (0.54) | CES1CES2LMNACA2CA4 | |
| SCHEMBL28785748 | 0.77 | CES1 (0.54) | CES1CES2LMNACA2CA4 | |
| SCHEMBL6262951 | 0.77 | CES2 (0.54) | CES1CES2LMNACA2CA4 | |
| SCHEMBL27539912 | 0.77 | CES2 (0.54) | CES1CES2LMNACA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150374861-A1 | KIT FOR TUMOR IMAGING | THOMAS JEFFERSON UNIVERSITY | 2015-12-31 | — | — | US | disclosed |
| EP-2956157-A1 | KIT FOR TUMOR IMAGING | Thomas Jefferson University (US) | 2015-12-23 | — | — | EP | disclosed |
| WO-2014126902-A1 | KIT FOR TUMOR IMAGING | THOMAS JEFFERSON UNIVERSITY (US) | 2014-08-21 | — | — | WO | disclosed |
| EP-0542216-A1 | Diaminomercapto (thio)ethers as complexing agents for nucleides applicable in nuclear medicine, process for the preparation of this complexes, and masking kits containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150374861-A1 | KIT FOR TUMOR IMAGING | ARG1, TIE1, TYR | CES1 3705/4885CES2 4799/4885LMNA 875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.