⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL956731 | 0.77 | — | — | |
| SCHEMBL28923734 | 0.73 | — | — | |
| SCHEMBL3114407 | 0.73 | — | — | |
| SCHEMBL2892756 | 0.73 | — | — | |
| Propane SCHEMBL28442519 | 0.71 | TSHR (0.33) | — | |
| Propane SCHEMBL28447008 | 0.71 | TSHR (0.33) | — | |
| SCHEMBL1119763 | 0.71 | — | — | |
| SCHEMBL4460742 | 0.69 | EPHX1 (0.38) | — | |
| SCHEMBL454657 | 0.69 | EPHX1 (0.38) | — | |
| SCHEMBL6364881 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640900-A | Preparation method of thiourethane optical material | KOC SOLUTION CO LTD | 2015-05-20 | — | — | CN | claimed |
| US-20070010023-A1 | Method of analysis of amine by mass spectrometry | NGUYEN HOA D | 2007-01-11 | — | — | US | claimed |
| US-20050014279-A1 | Method of analysis of amine by mass spectrometry | NGUYEN HOA DUC (US) | 2005-01-20 | — | — | US | claimed |
| JP-8253481-A | — | — | None | — | — | JP | disclosed |
| US-20250333385-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-10-30 | — | — | US | disclosed |
| CN-118994182-A | Seleno-, thio-or oxo-narcotine derivatives, their synthesis and their use in tumour therapy | 华东理工大学 | 2024-11-22 | — | — | CN | disclosed |
| US-20240132452-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-04-25 | — | — | US | disclosed |
| CN-115403584-B | 2-thio-2, 3-dihydropyrimidine-4-one derivatives, pharmaceutical compositions, preparation methods and applications thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| US-20230109968-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-04-13 | — | — | US | disclosed |
| CN-112694514-B | Pentacyclic triterpenoid TGR5 receptor agonist, and preparation method and application thereof | 中国科学院上海药物研究所 | 2022-09-23 | — | — | CN | disclosed |
| EP-3970721-A1 | DIARYLHYDANTOIN COMPOUNDS AS ANDROGEN RECEPTOR ANTAGONISTS FOR TREATMENT OF CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-03-23 | — | — | EP | disclosed |
| EP-0798295-A1 | NOVEL AMIDINONAPHTHYL DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |
| JP-H08253481-A | PRODUCTION OF CARBAPENEM COMPOUND | LEDERLE JAPAN LTD | 1996-10-01 | — | — | JP | disclosed |
| CN-1126735-A | composition for optical material and use thereof | MITSUI TOATSU CHEMICALS (JP) | 1996-07-17 | — | — | CN | disclosed |
| US-5489598-A | INHIBITS ADHESION OF MAC-1 TO ENDOTHELIAL CELLS, USEFUL FOR TREATING GASTRITIS INDUCED BY NONSTEROIDANTIINFLAMMATORY DRUGS IMFLAMMATORY BOWEL DISEASE OF ULCERATIVE COLITIS | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |
| EP-0682663-A1 | 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-22 | — | — | EP | disclosed |
| WO-1994018188-A1 | 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL[B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS | THE UPJOHN COMPANY (US) | 1994-08-18 | — | — | WO | disclosed |
| US-4833219-A | Preparation of substituted polysulfones by metalation | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 1989-05-23 | — | — | US | disclosed |
| US-4797457-A | POLYETHER COPOLYMERS CONTAINING SULFONES | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 1989-01-10 | — | — | US | disclosed |
| US-4656217-A | CURABLE CARBOXY-CONTAINING POLYMER MODIFIED BY AN UNSATURATED AZIRIDINE COMPOUND; ADHESIVES, CONCRETE SLABS; CASTINGS | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1987-04-07 | — | — | US | disclosed |