Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 4/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567320 | 0.74 | GRM4 (0.38) | MEN1MAPTKMT2AGAADRD1 | |
| SCHEMBL9567325 | 0.74 | GRM4 (0.38) | MEN1MAPTKMT2AGAADRD1 | |
| SCHEMBL9567332 | 0.73 | KMT2A (0.50) | MEN1MAPTKMT2AKDM4EDRD1 | |
| SCHEMBL9567329 | 0.73 | KMT2A (0.50) | MEN1MAPTKMT2AKDM4EDRD1 | |
| SCHEMBL11732162 | 0.73 | MEN1 (0.61) | MEN1MAPTKMT2AGAANPSR1 | |
| SCHEMBL9380509 | 0.73 | MEN1 (0.78) | MEN1MAPTKMT2AGAANPSR1 | |
| SCHEMBL14559413 | 0.72 | KMT2A (0.68) | MEN1MAPTKMT2AGAANPSR1 | |
| SCHEMBL28297921 | 0.70 | PDE4A (0.46) | MEN1MAPTKMT2AGAAAPP | |
| SCHEMBL28264345 | 0.69 | MEN1 (0.48) | MEN1MAPTKMT2AGAANPSR1 | |
| SCHEMBL9379237 | 0.69 | L3MBTL1 (0.47) | MEN1MAPTKMT2AGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532996-A1 | Diarylpyrazolinones | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |