Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PAM | P19021 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567414 | 1.00 | TSHR (0.46) | TSHRNR1I2PGRADORA3PTGS2 | |
| SCHEMBL27331787 | 0.87 | TSHR (0.47) | TSHRNR1I2PGRADORA3PTGS2 | |
| SCHEMBL6550916 | 0.87 | TSHR (0.52) | TSHRNR1I2PGRADORA3PTGS2 | |
| SCHEMBL27450682 | 0.87 | TSHR (0.52) | TSHRNR1I2PGRADORA3PTGS2 | |
| SCHEMBL6552702 | 0.87 | TSHR (0.52) | TSHRNR1I2PGRADORA3PTGS2 | |
| SCHEMBL6551855 | 0.85 | TSHR (0.55) | TSHRNR1I2PGRADORA3PTGS2 | |
| SCHEMBL27528104 | 0.85 | TSHR (0.55) | TSHRNR1I2PGRADORA3PTGS2 | |
| SCHEMBL6552434 | 0.85 | TSHR (0.55) | TSHRNR1I2PGRADORA3PTGS2 | |
| SCHEMBL448049 | 0.83 | ADRA2A (0.41) | TSHRNR1I2PGRADORA3PTGS2 | |
| SCHEMBL9122870 | 0.82 | TSHR (0.56) | TSHRNR1I2PGRADORA3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549344-A1 | Triazine derivatives as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-30 | — | — | EP | disclosed |