SCHEMBL9567415

SCHEMBL9567415

COc1nc(OC)nc(Oc2cccc(-c3ccccc3)c2C(=O)ON(C)C)n1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
FGFR1 P11362 1/20 0.39
SRC P12931 1/20 0.39
FGFR2 P21802 1/20 0.39
FGFR4 P22455 1/20 0.39
FGFR3 P22607 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9567436 0.88 NPSR1 (0.38) ALDH1A1SMN1; SMN2
SCHEMBL9032593 0.82 MAPT (0.40) ALDH1A1SMN1; SMN2KMT2A
SCHEMBL9567449 0.81 NPC1 (0.43) KMT2ASRC
SCHEMBL9567412 0.81 NPSR1 (0.44) ALDH1A1SMN1; SMN2
SCHEMBL8959287 0.80 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2
SCHEMBL8959295 0.80 CYP1A2 (0.55) ALDH1A1SMN1; SMN2
SCHEMBL9215188 0.79 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2
SCHEMBL9475471 0.78 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2
SCHEMBL9275700 0.78 NCEH1 (0.51) ALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL9754474 0.76 CYP2C9 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5247005-A None JP disclosed
JP-H05247005-A TRIAZINE DERIVATIVE, ITS PRODUCTION AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT SUMITOMO CHEM CO LTD 1993-09-24 JP disclosed
EP-0549344-A1 Triazine derivatives as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-30 EP disclosed