Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.63 |
| ▸ | HTR7 | P34969 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 6/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9264804 | 0.99 | HTR1A (0.65) | HTR1AHTR7SLC6A4KCNH2DRD2 | |
| SCHEMBL11820831 | 0.88 | HTR1A (0.79) | HTR1AHTR7SLC6A4KCNH2DRD2 | |
| SCHEMBL9567458 | 0.85 | HTR1A (0.49) | HTR1AHTR7SLC6A4KCNH2DRD2 | |
| SCHEMBL9367741 | 0.85 | HTR1A (0.74) | HTR1AHTR7SLC6A4KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL9262251 | 0.85 | HTR1A (0.48) | HTR1AHTR7SLC6A4KCNH2DRD2 | |
| SCHEMBL6589437 | 0.84 | HTR1A (0.71) | HTR1AHTR7SLC6A4KCNH2DRD2 | |
| SCHEMBL6355097 | 0.83 | HTR1A (0.62) | HTR1AHTR7SLC6A4KCNH2DRD2 | |
| SCHEMBL8824019 | 0.83 | HTR1A (0.57) | HTR1AHTR7SLC6A4KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL9377200 | 0.83 | HTR1A (0.61) | HTR1AHTR7SLC6A4KCNH2DRD2 | |
| SCHEMBL6588051 | 0.81 | HTR1A (0.67) | HTR1AHTR7SLC6A4KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548813-A1 | Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines | Bristol-Myers Squibb Company (US) | 1993-06-30 | — | — | EP | claimed |