Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9262251 | 0.99 | HTR1A (0.48) | HTR1AHTR7SLC6A4KCNH2MEN1 | |
| SCHEMBL9567460 | 0.85 | HTR1A (0.63) | HTR1AHTR7SLC6A4KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL9264804 | 0.84 | HTR1A (0.65) | HTR1AHTR7SLC6A4KCNH2DRD2 | |
| SCHEMBL6362332 | 0.79 | DRD2 (0.44) | HTR1AHTR7SLC6A4KCNH2DRD2 | |
| SCHEMBL9204485 | 0.78 | LMNA (0.46) | HTR1AHTR7MEN1LMNAKMT2A | |
| SCHEMBL6362295 | 0.77 | HTR1A (0.55) | HTR1AHTR7SLC6A4KCNH2DRD2 | |
| SCHEMBL19431749 | 0.76 | HTR1A (0.65) | HTR1AHTR7SLC6A4KMT2ADRD2 | |
| SCHEMBL6356579 | 0.75 | HTR1A (0.47) | HTR1AHTR7SLC6A4KCNH2MEN1 | |
| SCHEMBL9208142 | 0.75 | HTR1A (0.48) | HTR1ASLC6A4DRD2 | |
| SCHEMBL6356825 | 0.74 | HTR1A (0.53) | HTR1AHTR7SLC6A4KCNH2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548813-A1 | Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines | Bristol-Myers Squibb Company (US) | 1993-06-30 | — | — | EP | claimed |