Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607959 | 0.70 | CYP1A2 (0.35) | CYP1A2HIF1ATHRB | |
| SCHEMBL3058001 | 0.69 | KMT2A (0.35) | CYP1A2HIF1A | |
| SCHEMBL7469088 | 0.69 | CYP1A2 (0.33) | CYP1A2HIF1A | |
| SCHEMBL7472185 | 0.68 | CYP1A2 (0.33) | CYP1A2HIF1A | |
| SCHEMBL9636985 | 0.67 | CYP1A2 (0.33) | CYP1A2HIF1ATHRB | |
| SCHEMBL7470544 | 0.66 | MMP2 (0.33) | CYP1A2HIF1A | |
| SCHEMBL8552512 | 0.66 | MAPT (0.37) | — | |
| SCHEMBL13930678 | 0.65 | KDM4E (0.36) | — | |
| SCHEMBL7471984 | 0.65 | CYP1A2 (0.30) | CYP1A2HIF1A | |
| SCHEMBL10869465 | 0.64 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538691-A1 | Substituted tetrahydrothiophenes, methods for their preparation, and their use in pharmaceutical compositions | BAYER AG (DE) | 1993-04-28 | — | — | EP | disclosed |
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | disclosed |
| EP-0195346-A2 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1986-09-24 | — | — | EP | disclosed |
| EP-0005559-B1 | PHENYLAMINOTHIOPHENE ACETIC ACIDS, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-11-04 | — | — | EP | disclosed |
| EP-0005559-A1 | Phenylaminothiophene acetic acids, process for their preparation and medicaments containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1979-11-28 | — | — | EP | disclosed |