Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978101 | 0.78 | MAPT (0.38) | MAPTTP53SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9567770 | 0.66 | CYP1A2 (0.31) | — | |
| SCHEMBL2607959 | 0.59 | CYP1A2 (0.35) | MAPTKDM4E | |
| SCHEMBL7469088 | 0.58 | CYP1A2 (0.33) | — | |
| SCHEMBL5132106 | 0.58 | MAPT (0.50) | MAPTKDM4E | |
| SCHEMBL28885404 | 0.57 | TUBB4A (0.44) | MAPTTP53SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7472185 | 0.57 | CYP1A2 (0.33) | — | |
| SCHEMBL6862850 | 0.57 | MAPT (0.36) | MAPTKDM4E | |
| SCHEMBL16108807 | 0.56 | TDP1 (0.39) | TP53KDM4E | |
| SCHEMBL5675317 | 0.56 | KMT2A (0.53) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836603-A1 | SUBSTITUTED 1,3-DIOXAN-5-YLAMINO HETEROCYCLIC COMPOUNDS, METHODS FOR PREPARING THEM AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002264-A1 | SUBSTITUTED 1,3-DIOXAN-5-YLAMINO HETEROCYCLIC COMPOUNDS, METHODS FOR PREPARING THEM AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-01-23 | — | — | WO | disclosed |