SCHEMBL95679

SCHEMBL95679

C=CCOC(N)[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C[C@@H]1OP(=O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 17/20 0.44
P2RY4 P51582 10/20 0.44
DUT P33316 1/20 0.42
P2RY6 Q15077 5/20 0.42
POLA1 P09884 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1457060 0.83 P2RY2 (0.53) P2RY2P2RY4P2RY6
SCHEMBL4619792 0.82 DUT (0.50) P2RY2P2RY4DUTP2RY6POLA1
SCHEMBL95903 0.81 DUT (0.45) P2RY2P2RY4DUTP2RY6
SCHEMBL2811539 0.79 DUT (0.47) P2RY2P2RY4DUTP2RY6POLA1
SCHEMBL2811544 0.78 DUT (0.46) P2RY2P2RY4DUTP2RY6POLA1
SCHEMBL7906606 0.77 P2RY2 (0.52) P2RY2P2RY4DUTP2RY6POLA1
SCHEMBL7906610 0.77 P2RY2 (0.52) P2RY2P2RY4DUTP2RY6POLA1
SCHEMBL27341456 0.77 P2RY2 (0.58) P2RY2P2RY4DUTP2RY6POLA1
SCHEMBL29431049 0.75 DUT (0.56) P2RY2P2RY4DUTP2RY6POLA1
SCHEMBL8439448 0.75 DUT (0.50) P2RY2P2RY4DUTP2RY6POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351910-B2 Gene and protein expression properties of adherent stromal cells cultured in 3D PLURISTEM LTD (IL) 2019-07-16 US disclosed
US-20180369238-A1 DOPAMINE AGONISTS IN TREATING ALCOHOL USE DISORDERS ASSOCIATED WITH DOPAMINE RECEPTOR ACTIVITY MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2018-12-27 US disclosed
US-20180371542-A1 OPIOID RECEPTOR BLOCKADE IN TREATING ALCOHOL USE DISORDERS MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2018-12-27 US disclosed
EP-3133167-B1 METHODS RELATING TO FUSIONS OF ALK FOR DIAGNOSING CANCER INSIGHT GENETICS INC (US) 2018-09-12 EP disclosed
US-20180208993-A1 HIGHLY SENSITIVE METHODS FOR DETECTING BTK RESISTANCE MUTATIONS IN RNA AND DNA OHIO STATE INNOVATION FOUNDATION 2018-07-26 US disclosed
EP-1583843-B1 SINGLE PRIMER WHOLE GENOME AMPLIFICATION QIAGEN GMBH (DE) 2018-07-18 EP disclosed
EP-2432794-B1 TRANS-ACTING RNA SWITCHES THE RES FOUND OF STATE UNIV OF NEW YORK (US) 2017-08-30 EP disclosed
US-9719085-B2 Trans-acting RNA switches THE RESEARCH FOUNDATION OF THE UNIVERSITY OF NEW YORK (US) 2017-08-01 US disclosed
US-20170183743-A1 METHODS AND COMPOSITIONS RELATING TO FUSIONS OF ALK FOR DIAGNOSING AND TREATING CANCER INSIGHT GENETICS, INC. (US) 2017-06-29 US disclosed
US-9593366-B2 Individually synthesized primers to be used in whole genome amplification QIAGEN GAITHERSBURG, INC. (US) 2017-03-14 US disclosed
US-20040121338-A1 Real-time detection of rolling circle amplification products QIAGEN GMBH (DE) 2004-06-24 US disclosed
US-20040115643-A1 Thermodynamic equilibrium extension of primers YALE UNIVERSITY 2004-06-17 US disclosed
WO-2004027035-A2 RIBOSWITCHES, METHODS FOR THEIR USE, AND COMPOSITIONS FOR USE WITH RIBOSWITCHES. YALE UNIVERSITY (US) 2004-04-01 WO disclosed
US-20030228613-A1 Nucleic acid amplification QIAGEN GMBH (DE) 2003-12-11 US disclosed
US-6617137-B2 During replication at least one of the replicated strands is displaced from the genome by strand displacement replication of another replicated strand. MOLECULAR STAGING INC. 2003-09-09 US disclosed
WO-2003066908-A1 DETECTION METHOD USING DISSOCIATED ROLLING CIRCLE AMPLIFICATION MOLECULAR STAGING, INC. (US) 2003-08-14 WO disclosed
US-20030152932-A1 Detection method using dissociated rolling circle amplification QIAGEN GMBH (DE) 2003-08-14 US disclosed
US-20030143587-A1 Nucleic acid amplification MOLECULAR STAGING, INC. 2003-07-31 US disclosed
US-20030118998-A1 Nucleic acid amplification QIAGEN GMBH (DE) 2003-06-26 US disclosed
WO-2003033724-A2 NUCLEIC ACID AMPLIFICATION MOLECULAR STAGING, INC. (US) 2003-04-24 WO disclosed