Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | KDM6B | O15054 | 3/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4B | O94953 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050059 | 0.81 | TBXAS1 (0.38) | PTGIRTBXAS1KDM4CKDM5BKDM5A | |
| SCHEMBL8858470 | 0.81 | TBXAS1 (0.56) | PTGIRTBXAS1KDM4C | |
| SCHEMBL8858466 | 0.81 | TBXAS1 (0.56) | PTGIRTBXAS1KDM4C | |
| SCHEMBL9568066 | 0.72 | TBXAS1 (0.38) | PTGIRTBXAS1KDM4CKDM5BKDM5A | |
| SCHEMBL9568012 | 0.66 | TAOK1 (0.35) | PTGIRTBXAS1KDM4CKDM5BKDM5A | |
| SCHEMBL9568154 | 0.62 | CYP19A1 (0.31) | TBXAS1 | |
| SCHEMBL9048031 | 0.62 | MEN1 (0.39) | KDM4CKDM5BKDM5ACYP3A4ALDH1A1 | |
| SCHEMBL9568061 | 0.61 | PTGIR (0.36) | PTGIR | |
| SCHEMBL9047812 | 0.61 | PTGIR (0.65) | PTGIRTBXAS1KDM4C | |
| SCHEMBL9047804 | 0.61 | PTGIR (0.42) | PTGIRTBXAS1KDM4CKDM5BKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |