Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | UGCG | Q16739 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.43 |
| ▸ | KDM5A | P29375 | 2/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567971 | 0.89 | PRMT5 (0.53) | ALDH1A1UGCGPRMT5WDR77DHODH | |
| SCHEMBL9568037 | 0.88 | CNR1 (0.46) | CNR1ALDH1A1EPHX2DHODHL3MBTL1 | |
| SCHEMBL9568039 | 0.81 | UGCG (0.52) | ALDH1A1UGCGPRMT5WDR77L3MBTL1 | |
| SCHEMBL9568169 | 0.81 | PRMT5 (0.52) | CNR1ALDH1A1PRMT5WDR77EPHX2 | |
| SCHEMBL9049270 | 0.79 | PTGIR (0.59) | — | |
| SCHEMBL9567986 | 0.79 | UGCG (0.50) | ALDH1A1UGCGPRMT5WDR77DHODH | |
| SCHEMBL9568077 | 0.77 | TRPV1 (0.46) | ALDH1A1DHODHL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL9568008 | 0.77 | ALDH1A1 (0.51) | ALDH1A1UGCGEPHX2HTTKDM4C | |
| SCHEMBL3590904 | 0.76 | FFAR1 (0.52) | ALDH1A1L3MBTL1HTTKDM4CKDM5A | |
| SCHEMBL30301824 | 0.76 | FFAR1 (0.52) | ALDH1A1L3MBTL1HTTKDM4CKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |