SCHEMBL19985007

SCHEMBL19985007

CNC(=O)CC1CCc2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.51
WDR77 Q9BQA1 1/20 0.51
MTNR1A P48039 6/20 0.50
MTNR1B P49286 6/20 0.50
PDPK1 O15530 1/20 0.47
HTR6 P50406 1/20 0.44
FFAR1 O14842 1/20 0.44
ALDH1A1 P00352 1/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14356155 0.82 MTNR1B (0.50) PRMT5WDR77MTNR1AMTNR1BPDPK1
SCHEMBL6272803 0.82 MTNR1B (0.50) PRMT5WDR77MTNR1AMTNR1BPDPK1
SCHEMBL1470470 0.81 MTNR1A (0.50) PRMT5WDR77MTNR1AMTNR1BPDPK1
SCHEMBL1567606 0.80 MTNR1A (0.51) PRMT5WDR77MTNR1AMTNR1BPDPK1
SCHEMBL7847075 0.80 FFAR1 (0.62) PRMT5WDR77MTNR1AMTNR1BHTR6
SCHEMBL1470461 0.80 FFAR1 (0.62) PRMT5WDR77MTNR1AMTNR1BHTR6
SCHEMBL7845908 0.80 FFAR1 (0.62) PRMT5WDR77MTNR1AMTNR1BHTR6
SCHEMBL7683396 0.79 MTNR1A (0.48) PRMT5WDR77MTNR1AMTNR1BPDPK1
SCHEMBL6184833 0.79 HTR6 (0.51) PRMT5WDR77MTNR1AMTNR1BHTR6
SCHEMBL7296740 0.79 MTNR1A (0.50) PRMT5WDR77MTNR1AMTNR1BHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512843-B1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-10-20 EP disclosed
US-11136292-B2 Plant growth regulator compounds SYNGENTA PARTICIPATIONS AG (CH) 2021-10-05 US disclosed
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-10-31 US disclosed
WO-2018050477-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136292-B2 Plant growth regulator compounds FGF1, MST1, CDC20 PRMT5 3165/4885WDR77 3534/4885MTNR1A 1155/4885
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS FGF1, MST1, CDC20 PRMT5 3165/4885WDR77 3534/4885MTNR1A 1155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.