Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.46 |
| ▸ | KDM5A | P29375 | 2/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.46 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567972 | 0.91 | TAOK1 (0.48) | TAOK1KDM4CKDM5AKDM5BTAOK3 | |
| SCHEMBL9046057 | 0.85 | TBXAS1 (0.39) | TAOK1KDM4CKDM5AKDM5BTAOK3 | |
| SCHEMBL9568029 | 0.85 | TAOK1 (0.49) | TAOK1KDM4CKDM5AKDM5BTAOK3 | |
| SCHEMBL8858464 | 0.83 | TBXAS1 (0.57) | KDM4CTBXAS1 | |
| SCHEMBL9568013 | 0.83 | TAOK1 (0.44) | TAOK1KDM4CKDM5AKDM5BTAOK3 | |
| SCHEMBL9568050 | 0.81 | KDM4C (0.47) | TAOK1KDM4CKDM5AKDM5BTAOK3 | |
| SCHEMBL9567997 | 0.78 | HPGD (0.48) | TAOK1KDM4CKDM5AKDM5BTAOK3 | |
| SCHEMBL9567963 | 0.74 | ALDH1A1 (0.44) | KDM4CKDM5AKDM5BALDH1A1TRPV1 | |
| SCHEMBL8858624 | 0.74 | TBXAS1 (0.59) | KDM4CTBXAS1 | |
| SCHEMBL9567988 | 0.73 | TAOK1 (0.47) | TAOK1KDM4CKDM5AKDM5BTAOK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |